67.3 B12

67.3.1 Global tests

Type III ANOVA on main and interaction effects, and LM model summaries.

Prolactin
Chisq Df Pr(>Chisq)
(Intercept) 250.7924480 1 <0.0001 ***
Study 3.2136720 1 0.07 ns
f39_gdm_new 0.5754347 1 0.4 ns
BMI 3.3368238 1 0.07 ns
Ethnicity_cauc 105.4219556 1 <0.0001 ***
f10c_any_cig_1st_vst 49.1590682 1 <0.0001 ***
GA_samp 164.6323095 1 <0.0001 ***
Study:f39_gdm_new 1.8652579 1 0.2 ns
HPL
Chisq Df Pr(>Chisq)
(Intercept) 150.8759535 1 <0.0001 ***
Study 7.3986291 1 0.007 **
f39_gdm_new 0.4357432 1 0.5 ns
BMI 236.2094019 1 <0.0001 ***
Ethnicity_cauc 5.5165373 1 0.02 *
f10c_any_cig_1st_vst 0.9176455 1 0.3 ns
GA_samp 2601.9722143 1 <0.0001 ***
Study:f39_gdm_new 1.4845286 1 0.2 ns
GH2
Chisq Df Pr(>Chisq)
(Intercept) 251.096669 1 <0.0001 ***
Study 1.107622 1 0.3 ns
f39_gdm_new 1.386104 1 0.2 ns
BMI 87.622496 1 <0.0001 ***
Ethnicity_cauc 3.246832 1 0.07 ns
f10c_any_cig_1st_vst 1.039153 1 0.3 ns
GA_samp 1032.266869 1 <0.0001 ***
Study:f39_gdm_new 3.376951 1 0.07 ns
Insulin
model term df1 df2 F.ratio Chisq p.value
1 Study 1 Inf 21.326 21.326 <0.0001 ***
3 f39_gdm_new 1 Inf 33.726 33.726 <0.0001 ***
4 BMI 1 Inf 330.722 330.722 <0.0001 ***
5 Ethnicity_cauc 1 Inf 25.046 25.046 <0.0001 ***
6 f10c_any_cig_1st_vst 1 Inf 3.158 3.158 0.08 ns
7 GA_samp 1 Inf 2.506 2.506 0.1 ns
2 Study:f39_gdm_new 1 Inf 4.089 4.089 0.04 *
HOMA.IR
model term df1 df2 F.ratio Chisq p.value
1 Study 1 Inf 36.051 36.051 <0.0001 ***
3 f39_gdm_new 1 Inf 32.027 32.027 <0.0001 ***
4 BMI 1 Inf 316.807 316.807 <0.0001 ***
5 Ethnicity_cauc 1 Inf 24.882 24.882 <0.0001 ***
6 f10c_any_cig_1st_vst 1 Inf 2.618 2.618 0.1 ns
7 GA_samp 1 Inf 1.602 1.602 0.2 ns
2 Study:f39_gdm_new 1 Inf 4.361 4.361 0.04 *
GLUC3_mmol.L
model term df1 df2 F.ratio Chisq p.value
1 Study 1 Inf 53.182 53.182 <0.0001 ***
3 f39_gdm_new 1 Inf 4.345 4.345 0.04 *
4 BMI 1 Inf 11.449 11.449 0.0007 ***
5 Ethnicity_cauc 1 Inf 0.718 0.718 0.4 ns
6 f10c_any_cig_1st_vst 1 Inf 0.028 0.028 0.9 ns
7 GA_samp 1 Inf 0.278 0.278 0.6 ns
2 Study:f39_gdm_new 1 Inf 1.558 1.558 0.2 ns

67.3.2 Model summary

Ratio of Geometric means (95% CI)

Prolactin
Var Effect P
(Intercept) 2.58 (2.21, 2.96) <0.0001
B12 0.00 (-0.00, 0.00) 0.05
f39_gdm_newGDM -0.14 (-0.42, 0.15) 0.35
StudySTOP -0.02 (-0.20, 0.16) 0.84
GA_samp 0.14 (0.12, 0.16) <0.0001
B12:f39_gdm_newGDM 0.00 (-0.00, 0.00) 0.67
f39_gdm_newGDM:StudySTOP 0.16 (-0.06, 0.39) 0.16
B12:StudySTOP -0.00 (-0.00, 0.00) 0.87
HPL
Var Effect P
(Intercept) 0.57 (0.37, 0.76) <0.0001
B12 0.00 (-0.00, 0.00) 0.08
f39_gdm_newGDM -0.01 (-0.16, 0.13) 0.86
StudySTOP 0.09 (-0.01, 0.19) 0.07
GA_samp 0.29 (0.28, 0.30) <0.0001
B12:f39_gdm_newGDM -0.00 (-0.00, 0.00) 0.22
f39_gdm_newGDM:StudySTOP 0.08 (-0.04, 0.19) 0.18
B12:StudySTOP 0.00 (-0.00, 0.00) 0.96
GH2
Var Effect P
(Intercept) -2.81 (-3.07, -2.54) <0.0001
B12 0.00 (0.00, 0.00) <0.0001
f39_gdm_newGDM -0.18 (-0.39, 0.02) 0.09
StudySTOP 0.10 (-0.04, 0.23) 0.16
GA_samp 0.26 (0.25, 0.28) <0.0001
B12:f39_gdm_newGDM 0.00 (-0.00, 0.00) 0.82
f39_gdm_newGDM:StudySTOP 0.19 (0.02, 0.35) 0.03
B12:StudySTOP -0.00 (-0.00, -0.00) 0.02
Insulin
Var Effect P
(Intercept) 2.56 (2.07, 3.06) <0.0001
B12 -0.00 (-0.00, 0.00) 0.13
f39_gdm_newGDM 1.24 (0.32, 2.17) 0.009
StudySTOP -0.30 (-0.56, -0.03) 0.03
GA_samp 0.02 (-0.01, 0.05) 0.24
B12:f39_gdm_newGDM -0.00 (-0.00, 0.00) 0.25
f39_gdm_newGDM:StudySTOP -0.61 (-1.61, 0.39) 0.23
B12:StudySTOP 0.00 (-0.00, 0.00) 0.60
B12:f39_gdm_newGDM:StudySTOP 0.00 (-0.00, 0.00) 0.42
HOMA.IR
Var Effect P
(Intercept) 1.19 (0.67, 1.71) <0.0001
B12 -0.00 (-0.00, 0.00) 0.16
f39_gdm_newGDM 1.28 (0.24, 2.32) 0.02
StudySTOP -0.45 (-0.73, -0.16) 0.002
GA_samp 0.01 (-0.02, 0.04) 0.38
B12:f39_gdm_newGDM -0.00 (-0.00, 0.00) 0.36
f39_gdm_newGDM:StudySTOP -0.60 (-1.71, 0.51) 0.29
B12:StudySTOP 0.00 (-0.00, 0.00) 0.63
B12:f39_gdm_newGDM:StudySTOP 0.00 (-0.00, 0.00) 0.55
GLUC3_mmol.L
Var Effect P
(Intercept) 1.74 (1.65, 1.84) <0.0001
B12 -0.00 (-0.00, 0.00) 0.16
f39_gdm_newGDM 0.11 (-0.04, 0.26) 0.15
StudySTOP -0.15 (-0.20, -0.11) <0.0001
GA_samp -0.00 (-0.01, 0.00) 0.46
B12:f39_gdm_newGDM 0.00 (-0.00, 0.00) 0.85
f39_gdm_newGDM:StudySTOP -0.08 (-0.20, 0.03) 0.16
B12:StudySTOP 0.00 (-0.00, 0.00) 0.55

67.3.3 Estimated means

Estimated marginal means (or adjusted means) adjusted for GA at sampling.

Results are averaged over the levels of B12 concentration (pM) and may be misleading when interaction term is involved.

Prolactin
Study f39_gdm_new response SE df lower.CL upper.CL
SCOPE non-GDM 99.48282 7.527503 90.84823 85.59952 115.6178
STOP non-GDM 96.25826 6.870852 72.18811 83.49184 110.9767
SCOPE GDM 91.16056 11.371799 545.10747 71.34899 116.4732
STOP GDM 103.59983 8.934423 149.87271 87.36834 122.8469
HPL
Study f39_gdm_new response SE df lower.CL upper.CL
SCOPE non-GDM 90.26660 2.468158 171.5369 85.52386 95.27234
STOP non-GDM 99.14269 2.415073 110.2077 94.47037 104.04610
SCOPE GDM 82.56036 4.512539 818.3553 74.16144 91.91047
STOP GDM 97.86903 3.519895 414.0479 91.18886 105.03858
GH2
Study f39_gdm_new response SE df lower.CL upper.CL
SCOPE non-GDM 2.436758 0.0725078 439.7072 2.298340 2.583512
STOP non-GDM 2.314613 0.0556715 242.8413 2.207509 2.426912
SCOPE GDM 2.072222 0.1583053 1395.6170 1.783829 2.407240
STOP GDM 2.371184 0.1004585 760.9642 2.181953 2.576826
Insulin
Study f39_gdm_new response SE df asymp.LCL asymp.UCL
SCOPE non-GDM 13.77965 0.7143520 Inf 12.44832 15.25335
STOP non-GDM 10.98705 0.4168576 Inf 10.19966 11.83522
SCOPE GDM 27.81263 3.7909330 Inf 21.29222 36.32980
STOP GDM 18.16724 1.3699737 Inf 15.67114 21.06091
HOMA.IR
Study f39_gdm_new response SE df asymp.LCL asymp.UCL
SCOPE non-GDM 3.336606 0.1841394 Inf 2.994533 3.717755
STOP non-GDM 2.287398 0.0913192 Inf 2.115239 2.473569
SCOPE GDM 7.442549 1.1042775 Inf 5.564496 9.954455
STOP GDM 3.907561 0.3165887 Inf 3.333817 4.580044
GLUC3_mmol.L
Study f39_gdm_new response SE df asymp.LCL asymp.UCL
SCOPE non-GDM 5.402700 0.0546200 Inf 5.296700 5.510821
STOP non-GDM 4.703314 0.0358930 Inf 4.633488 4.774191
SCOPE GDM 6.070570 0.3237354 Inf 5.468094 6.739426
STOP GDM 4.866900 0.0625328 Inf 4.745869 4.991019

67.3.4 Comparisons

67.3.4.1 Within Groups

Effect for every 100 unit increase in B12 concentration (pM).
Hormone Contrast Study f39_gdm_new Ratio of Geometric means (95% CI) P-value
Prolactin B12366 / B12266 SCOPE non-GDM 1.044 (0.999, 1.092) 0.05
Prolactin B12366 / B12266 STOP non-GDM 1.040 (1.007, 1.074) 0.02
Prolactin B12366 / B12266 SCOPE GDM 1.061 (0.978, 1.150) 0.2
Prolactin B12366 / B12266 STOP GDM 1.056 (0.989, 1.128) 0.1
HPL B12366 / B12266 SCOPE non-GDM 1.022 (0.998, 1.046) 0.08
HPL B12366 / B12266 STOP non-GDM 1.022 (1.005, 1.041) 0.01
HPL B12366 / B12266 SCOPE GDM 0.997 (0.955, 1.041) 0.9
HPL B12366 / B12266 STOP GDM 0.998 (0.963, 1.034) 0.9
GH2 B12366 / B12266 SCOPE non-GDM 1.073 (1.038, 1.109) <0.0001
GH2 B12366 / B12266 STOP non-GDM 1.024 (1.000, 1.049) 0.05
GH2 B12366 / B12266 SCOPE GDM 1.080 (1.016, 1.147) 0.01
GH2 B12366 / B12266 STOP GDM 1.031 (0.981, 1.083) 0.2
Insulin B12366 / B12266 SCOPE non-GDM 0.948 (0.885, 1.016) 0.1
Insulin B12366 / B12266 STOP non-GDM 0.969 (0.925, 1.016) 0.2
Insulin B12366 / B12266 SCOPE GDM 0.799 (0.600, 1.064) 0.1
Insulin B12366 / B12266 STOP GDM 0.929 (0.841, 1.026) 0.1
HOMA.IR B12366 / B12266 SCOPE non-GDM 0.948 (0.880, 1.021) 0.2
HOMA.IR B12366 / B12266 STOP non-GDM 0.969 (0.922, 1.018) 0.2
HOMA.IR B12366 / B12266 SCOPE GDM 0.815 (0.594, 1.117) 0.2
HOMA.IR B12366 / B12266 STOP GDM 0.925 (0.831, 1.029) 0.1
GLUC3_mmol.L B12366 / B12266 SCOPE non-GDM 0.991 (0.979, 1.004) 0.2
GLUC3_mmol.L B12366 / B12266 STOP non-GDM 0.996 (0.988, 1.003) 0.3
GLUC3_mmol.L B12366 / B12266 SCOPE GDM 0.994 (0.964, 1.024) 0.7
GLUC3_mmol.L B12366 / B12266 STOP GDM 0.998 (0.977, 1.020) 0.9

67.3.4.2 Between Groups

Below are comparisons of the differences in the change in B12 concentration (pM) between groups. I.e. whether the change in B12 concentration (pM) are different between groups.

Prolactin
contrast ratio SE df lower.CL upper.CL p.value
SCOPE/SCOPE (Overall) 0.9913717 0.0545354 2067.758 0.8899886 1.104304 0.875 ns
STOP/SCOPE (non-GDM) 0.9956765 0.0273861 2067.758 0.9433921 1.050859 0.875 ns
STOP/SCOPE (GDM) 0.9956765 0.0273861 2067.758 0.9433921 1.050859 0.875 ns
GDM/non-GDM (SCOPE) 1.0156870 0.0371835 2042.467 0.9453216 1.091290 0.671 ns
GDM/non-GDM (STOP) 1.0156870 0.0371835 2042.467 0.9453216 1.091290 0.671 ns
HPL
contrast ratio SE df lower.CL upper.CL p.value
SCOPE/SCOPE (Overall) 1.0014580 0.0295309 1931.787 0.9451851 1.061081 0.961 ns
STOP/SCOPE (non-GDM) 1.0007287 0.0147547 1931.787 0.9722063 1.030088 0.961 ns
STOP/SCOPE (GDM) 1.0007287 0.0147547 1931.787 0.9722063 1.030088 0.961 ns
GDM/non-GDM (SCOPE) 0.9763306 0.0192592 1973.738 0.9392813 1.014841 0.225 ns
GDM/non-GDM (STOP) 0.9763306 0.0192592 1973.738 0.9392813 1.014841 0.225 ns
GH2
contrast ratio SE df lower.CL upper.CL p.value
SCOPE/SCOPE (Overall) 0.9111097 0.0372634 2095.061 0.8408864 0.9871974 0.023 *
STOP/SCOPE (non-GDM) 0.9545206 0.0195194 2095.061 0.9169986 0.9935781 0.023 *
STOP/SCOPE (GDM) 0.9545206 0.0195194 2095.061 0.9169986 0.9935781 0.023 *
GDM/non-GDM (SCOPE) 1.0064190 0.0275758 2103.809 0.9537676 1.0619770 0.815 ns
GDM/non-GDM (STOP) 1.0064190 0.0275758 2103.809 0.9537676 1.0619770 0.815 ns
Insulin
contrast ratio SE df asymp.LCL asymp.UCL p.value
SCOPE/SCOPE (Overall) 1.1891756 0.1906466 Inf 0.8685259 1.628205 0.280 ns
STOP/SCOPE (non-GDM) 1.0222629 0.0433951 Inf 0.9406521 1.110954 0.604 ns
STOP/SCOPE (GDM) 1.1632777 0.1798378 Inf 0.8591940 1.574982 0.328 ns
GDM/non-GDM (SCOPE) 0.8423908 0.1265802 Inf 0.6274940 1.130883 0.254 ns
GDM/non-GDM (STOP) 0.9585934 0.0535768 Inf 0.8591319 1.069570 0.449 ns
HOMA.IR
contrast ratio SE df asymp.LCL asymp.UCL p.value
SCOPE/SCOPE (Overall) 1.1596192 0.2039332 Inf 0.8215258 1.636853 0.400 ns
STOP/SCOPE (non-GDM) 1.0217772 0.0463690 Inf 0.9348201 1.116823 0.635 ns
STOP/SCOPE (GDM) 1.1349042 0.1928267 Inf 0.8134581 1.583373 0.456 ns
GDM/non-GDM (SCOPE) 0.8593715 0.1420847 Inf 0.6215084 1.188269 0.359 ns
GDM/non-GDM (STOP) 0.9545175 0.0572632 Inf 0.8486308 1.073616 0.438 ns
GLUC3_mmol.L
contrast ratio SE df asymp.LCL asymp.UCL p.value
SCOPE/SCOPE (Overall) 1.009181 0.0155431 Inf 0.9791723 1.040109 0.553 ns
STOP/SCOPE (non-GDM) 1.004580 0.0077361 Inf 0.9895313 1.019858 0.553 ns
STOP/SCOPE (GDM) 1.004580 0.0077361 Inf 0.9895313 1.019858 0.553 ns
GDM/non-GDM (SCOPE) 1.002406 0.0127711 Inf 0.9776852 1.027752 0.850 ns
GDM/non-GDM (STOP) 1.002406 0.0127711 Inf 0.9776852 1.027752 0.850 ns

67.3.5 Estimated means (50 unit increase)

Estimated marginal means (or adjusted means) adjusted for GA at sampling.

Results are averaged over the levels of B12 concentration (pM) and may be misleading when interaction term is involved.

Prolactin
Study f39_gdm_new response SE df lower.CL upper.CL
SCOPE non-GDM 98.40719 7.379890 87.68820 84.78112 114.2233
STOP non-GDM 95.32069 6.798638 71.96751 82.68715 109.8845
SCOPE GDM 89.82470 11.103764 530.19810 70.45843 114.5140
STOP GDM 102.19232 8.780994 147.75222 86.23305 121.1052
HPL
Study f39_gdm_new response SE df lower.CL upper.CL
SCOPE non-GDM 89.78496 2.407079 159.1047 85.15468 94.66702
STOP non-GDM 98.59574 2.398004 109.5640 93.95596 103.46463
SCOPE GDM 82.61309 4.461095 808.5369 74.30451 91.85071
STOP GDM 97.91371 3.500391 404.8910 91.26874 105.04249
GH2
Study f39_gdm_new response SE df lower.CL upper.CL
SCOPE non-GDM 2.394278 0.0688602 393.2630 2.262654 2.533559
STOP non-GDM 2.300881 0.0551683 240.6173 2.194733 2.412163
SCOPE GDM 2.032842 0.1535026 1385.4263 1.752961 2.357411
STOP GDM 2.353349 0.0987469 746.1677 2.167264 2.555412
Insulin
Study f39_gdm_new response SE df asymp.LCL asymp.UCL
SCOPE non-GDM 13.96429 0.6920242 Inf 12.67174 15.38869
STOP non-GDM 11.07315 0.4138377 Inf 10.29104 11.91470
SCOPE GDM 29.42012 4.0226695 Inf 22.50391 38.46191
STOP GDM 18.50421 1.3916351 Inf 15.96816 21.44304
HOMA.IR
Study f39_gdm_new response SE df asymp.LCL asymp.UCL
SCOPE non-GDM 3.381458 0.1782188 Inf 3.049592 3.749440
STOP non-GDM 2.305694 0.0907315 Inf 2.134549 2.490562
SCOPE GDM 7.833855 1.1876586 Inf 5.820072 10.544420
STOP GDM 3.984922 0.3226905 Inf 3.400097 4.670338
GLUC3_mmol.L
Study f39_gdm_new response SE df asymp.LCL asymp.UCL
SCOPE non-GDM 5.414391 0.0518294 Inf 5.313754 5.516934
STOP non-GDM 4.708110 0.0358237 Inf 4.638418 4.778849
SCOPE GDM 6.080052 0.3296930 Inf 5.467019 6.761827
STOP GDM 4.868938 0.0624862 Inf 4.747994 4.992961

67.3.6 Comparisons (50 unit increase)

67.3.6.1 Within Groups

Effect for every 50 unit increase in B12 concentration (pM).
Hormone Contrast Study f39_gdm_new Ratio of Geometric means (95% CI) P-value
Prolactin B12316 / B12266 SCOPE non-GDM 1.022 (1.000, 1.045) 0.05
Prolactin B12316 / B12266 STOP non-GDM 1.020 (1.003, 1.036) 0.02
Prolactin B12316 / B12266 SCOPE GDM 1.030 (0.989, 1.073) 0.2
Prolactin B12316 / B12266 STOP GDM 1.028 (0.994, 1.062) 0.1
HPL B12316 / B12266 SCOPE non-GDM 1.011 (0.999, 1.023) 0.08
HPL B12316 / B12266 STOP non-GDM 1.011 (1.002, 1.020) 0.01
HPL B12316 / B12266 SCOPE GDM 0.999 (0.977, 1.020) 0.9
HPL B12316 / B12266 STOP GDM 0.999 (0.981, 1.017) 0.9
GH2 B12316 / B12266 SCOPE non-GDM 1.036 (1.019, 1.053) <0.0001
GH2 B12316 / B12266 STOP non-GDM 1.012 (1.000, 1.024) 0.05
GH2 B12316 / B12266 SCOPE GDM 1.039 (1.008, 1.071) 0.01
GH2 B12316 / B12266 STOP GDM 1.015 (0.990, 1.041) 0.2
Insulin B12316 / B12266 SCOPE non-GDM 0.974 (0.941, 1.008) 0.1
Insulin B12316 / B12266 STOP non-GDM 0.985 (0.962, 1.008) 0.2
Insulin B12316 / B12266 SCOPE GDM 0.894 (0.774, 1.031) 0.1
Insulin B12316 / B12266 STOP GDM 0.964 (0.917, 1.013) 0.1
HOMA.IR B12316 / B12266 SCOPE non-GDM 0.974 (0.938, 1.010) 0.2
HOMA.IR B12316 / B12266 STOP non-GDM 0.984 (0.960, 1.009) 0.2
HOMA.IR B12316 / B12266 SCOPE GDM 0.903 (0.771, 1.057) 0.2
HOMA.IR B12316 / B12266 STOP GDM 0.962 (0.912, 1.014) 0.1
GLUC3_mmol.L B12316 / B12266 SCOPE non-GDM 0.996 (0.990, 1.002) 0.2
GLUC3_mmol.L B12316 / B12266 STOP non-GDM 0.998 (0.994, 1.002) 0.3
GLUC3_mmol.L B12316 / B12266 SCOPE GDM 0.997 (0.982, 1.012) 0.7
GLUC3_mmol.L B12316 / B12266 STOP GDM 0.999 (0.988, 1.010) 0.9

67.3.6.2 Between Groups

Below are comparisons of the differences in the change in B12 concentration (pM) between groups. I.e. whether the change in B12 concentration (pM) are different between groups.

Prolactin
contrast ratio SE df lower.CL upper.CL p.value
SCOPE/SCOPE (Overall) 0.9956765 0.0273861 2067.758 0.9433921 1.050859 0.875 ns
STOP/SCOPE (non-GDM) 0.9978359 0.0137227 2067.758 0.9712837 1.025114 0.875 ns
STOP/SCOPE (GDM) 0.9978359 0.0137227 2067.758 0.9712837 1.025114 0.875 ns
GDM/non-GDM (SCOPE) 1.0078130 0.0184476 2042.467 0.9722765 1.044648 0.671 ns
GDM/non-GDM (STOP) 1.0078130 0.0184476 2042.467 0.9722765 1.044648 0.671 ns
HPL
contrast ratio SE df lower.CL upper.CL p.value
SCOPE/SCOPE (Overall) 1.0007287 0.0147547 1931.787 0.9722063 1.030088 0.961 ns
STOP/SCOPE (non-GDM) 1.0003643 0.0073747 1931.787 0.9860052 1.014933 0.961 ns
STOP/SCOPE (GDM) 1.0003643 0.0073747 1931.787 0.9860052 1.014933 0.961 ns
GDM/non-GDM (SCOPE) 0.9880944 0.0097456 1973.738 0.9691653 1.007393 0.225 ns
GDM/non-GDM (STOP) 0.9880944 0.0097456 1973.738 0.9691653 1.007393 0.225 ns
GH2
contrast ratio SE df lower.CL upper.CL p.value
SCOPE/SCOPE (Overall) 0.9545206 0.0195194 2095.061 0.9169986 0.9935781 0.023 *
STOP/SCOPE (non-GDM) 0.9769957 0.0099895 2095.061 0.9576004 0.9967839 0.023 *
STOP/SCOPE (GDM) 0.9769957 0.0099895 2095.061 0.9576004 0.9967839 0.023 *
GDM/non-GDM (SCOPE) 1.0032044 0.0137439 2103.809 0.9766102 1.0305227 0.815 ns
GDM/non-GDM (STOP) 1.0032044 0.0137439 2103.809 0.9766102 1.0305227 0.815 ns
Insulin
contrast ratio SE df asymp.LCL asymp.UCL p.value
SCOPE/SCOPE (Overall) 1.0904933 0.0874130 Inf 0.9319474 1.276012 0.280 ns
STOP/SCOPE (non-GDM) 1.0110702 0.0214600 Inf 0.9698722 1.054018 0.604 ns
STOP/SCOPE (GDM) 1.0785535 0.0833699 Inf 0.9269272 1.254983 0.328 ns
GDM/non-GDM (SCOPE) 0.9178185 0.0689571 Inf 0.7921452 1.063430 0.254 ns
GDM/non-GDM (STOP) 0.9790778 0.0273609 Inf 0.9268937 1.034200 0.449 ns
HOMA.IR
contrast ratio SE df asymp.LCL asymp.UCL p.value
SCOPE/SCOPE (Overall) 1.0768562 0.0946892 Inf 0.9063806 1.279395 0.400 ns
STOP/SCOPE (non-GDM) 1.0108300 0.0229361 Inf 0.9668610 1.056798 0.635 ns
STOP/SCOPE (GDM) 1.0653188 0.0905019 Inf 0.9019191 1.258322 0.456 ns
GDM/non-GDM (SCOPE) 0.9270229 0.0766349 Inf 0.7883581 1.090078 0.359 ns
GDM/non-GDM (STOP) 0.9769941 0.0293058 Inf 0.9212116 1.036155 0.438 ns
GLUC3_mmol.L
contrast ratio SE df asymp.LCL asymp.UCL p.value
SCOPE/SCOPE (Overall) 1.004580 0.0077361 Inf 0.9895313 1.019858 0.553 ns
STOP/SCOPE (non-GDM) 1.002287 0.0038592 Inf 0.9947519 1.009880 0.553 ns
STOP/SCOPE (GDM) 1.002287 0.0038592 Inf 0.9947519 1.009880 0.553 ns
GDM/non-GDM (SCOPE) 1.001202 0.0063779 Inf 0.9887796 1.013781 0.850 ns
GDM/non-GDM (STOP) 1.001202 0.0063779 Inf 0.9887796 1.013781 0.850 ns

67.3.7 Diagnostics

Model diagnositcs.

Diagnositcs for PRL (ng/ml)

Diagnositcs for hPL (μg/ml)

Diagnositcs for GH2 (ng/ml)

Diagnositcs for Insulin (uU/ml)

Diagnositcs for HOMA-IR

Diagnositcs for Glucose (mmol/L)

67.3.8 Plots